验证数据展示
产品信息
27504-1-PBS targets PSMD8 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.
经测试应用 | WB, IF/ICC, Indirect ELISA Application Description |
经测试反应性 | human, mouse |
免疫原 | PSMD8 fusion protein Ag26567 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 |
别名 | |
计算分子量 | 257 aa, 30 kDa |
观测分子量 | 30 kDa |
GenBank蛋白编号 | BC001164 |
基因名称 | PSMD8 |
Gene ID (NCBI) | 5714 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | P48556 |
储存缓冲液 | PBS only, pH 7.3. |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
The Proteasome 26S Subunit, Non-ATPase (PSMD) gene family, which includes the PSMD1 to PSMD14, regulate ubiqutinated protein breakdown in circulation as well as tumorigenesis. Studies have shown that PSMD8 interacts with the sperm adhesin AQN1 to limit polyfertilization. PSMD8 was more expressed in normal skeletal muscle, cardiac muscle, and tongue muscle; among malignant tumors, PSMD8 was expressed in ovarian cancer, testicular cancer, glioma, and melanoma(PMID:37349676).