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验证数据展示

  • WB analysis using 25799-1-AP (same clone as 25799-1-PBS)

    WB analysis using 25799-1-AP (same clone as 25799-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 25799-1-AP (PLA2G12B antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 25799-1-PBS in a different storage buffer formulation.

  • WB analysis of HepG2 using 25799-1-AP (same clone as 25799-1-PBS)

    WB analysis of HepG2 using 25799-1-AP (same clone as 25799-1-PBS)

    WB result of PLA2G12B antibody (25799-1-AP; 1:400; incubated at room temperature for 1.5 hours) with sh-Control and sh-PLA2G12B transfected HepG2 cells. This data was developed using the same antibody clone with 25799-1-PBS in a different storage buffer formulation.

  • WB analysis of HuH-7 using 25799-1-AP (same clone as 25799-1-PBS)

    WB analysis of HuH-7 using 25799-1-AP (same clone as 25799-1-PBS)

    WB result of PLA2G12B antibody (25799-1-AP; 1:400; incubated at room temperature for 1.5 hours) with sh-Control and sh-PLA2G12B transfected HuH-7 cells. This data was developed using the same antibody clone with 25799-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

PLA2G12B Polyclonal antibody, PBS Only

PLA2G12B Polyclonal Antibody for WB, Indirect ELISA
Cat No. 25799-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, Indirect ELISA

别名

FKSG71, Group XIIB secretory phospholipase A2-like protein, Group XIII secretory phospholipase A2-like protein, GXIIB, GXIII sPLA2 like

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

25799-1-PBS targets PLA2G12B in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 PLA2G12B fusion protein Ag22877 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 phospholipase A2, group XIIB
别名 FKSG71, Group XIIB secretory phospholipase A2-like protein, Group XIII secretory phospholipase A2-like protein, GXIIB, GXIII sPLA2 like
计算分子量 195 aa, 22 kDa
观测分子量21-22 kDa
GenBank蛋白编号BC111946
基因名称 PLA2G12B
Gene ID (NCBI) 84647
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9BX93
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Phospholipase A2 (PLA2) enzymes catalyze hydrolysis of glycolipids to release free fatty acids and lysophospholipids. PLA2G12B is a secreted group XIIB secretory phospholipase A2-like protein belonging to the PLA2 family, but it is catalytically inactive due to an amino acid change in its active site and has altered phospholipid-binding properties (PMID: 14516201). It is located outside the cell membranes and strongly expressed in liver, small intestine and kidney, and recently reports revealed that Pla2g12b gene may be implicated in HDL cholesterol levels and metabolism (PMID: 22912808). The calculated molecular weight of PLA2G12B is 21 kDa.