验证数据展示
产品信息
20933-1-PBS targets PHIP in WB, IF/ICC, IP, Indirect ELISA applications and shows reactivity with human, mouse samples.
经测试应用 | WB, IF/ICC, IP, Indirect ELISA Application Description |
经测试反应性 | human, mouse |
免疫原 | PHIP fusion protein Ag14968 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | pleckstrin homology domain interacting protein |
别名 | |
计算分子量 | 1821 aa, 207 kDa |
观测分子量 | 207 kDa |
GenBank蛋白编号 | BC008909 |
基因名称 | PHIP |
Gene ID (NCBI) | 55023 |
RRID | AB_10733522 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | Q8WWQ0 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
PHIP is a protein that binds to the insulin receptor substrate 1 protein and regulates glucose transporter translocation in skeletal muscle cells. PHIP may also regulate growth and survival of pancreatic beta cells. Elevated copy number of this gene may be associated with melanoma severity and the encoded protein may promote melanoma metastasis in human patients.