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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 21084-1-AP (same clone as 21084-1-PBS)

    WB analysis using 21084-1-AP (same clone as 21084-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 21084-1-AP (PDZD7 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21084-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse eye using 21084-1-AP (same clone as 21084-1-PBS)

    IHC staining of mouse eye using 21084-1-AP (same clone as 21084-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse eye tissue slide using 21084-1-AP (PDZD7 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21084-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse eye using 21084-1-AP (same clone as 21084-1-PBS)

    IHC staining of mouse eye using 21084-1-AP (same clone as 21084-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse eye tissue slide using 21084-1-AP (PDZD7 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21084-1-PBS in a different storage buffer formulation.

PDZD7 Polyclonal antibody, PBS Only

PDZD7 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 21084-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IHC, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

21084-1-PBS targets PDZD7 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原 PDZD7 fusion protein Ag15318 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 PDZ domain containing 7
别名
计算分子量 517 aa, 56 kDa
观测分子量55 kDa
GenBank蛋白编号BC029054
基因名称 PDZD7
Gene ID (NCBI) 79955
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9H5P4
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

PDZD7, also known as PDZK7, is essential in organizing the USH2 complex at stereocilia ankle links and blocks inhibition of adenylate cyclase activity mediated by ADGRV1. PDZD7 encodes a PDZ domain-containing scaffold protein that is highly expressed in hair cells of the inner ear. PDZD7 is also expressed in the cilia of photoreceptors (PMID: 33530996). Dysfunction or mutations of PDZD7 result in Usher syndrome type 2 (USH2) and Autosomal recessive non-syndromic hearing loss(ARNSHL) (PMID: 29048736, 20440071).