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验证数据展示

  • IHC staining of human pituitary using 18041-1-AP (same clone as 18041-1-PBS)

    IHC staining of human pituitary using 18041-1-AP (same clone as 18041-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human pituitary tissue slide using 18041-1-AP (OXT antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 18041-1-PBS in a different storage buffer formulation.

  • IHC staining of human pituitary using 18041-1-AP (same clone as 18041-1-PBS)

    IHC staining of human pituitary using 18041-1-AP (same clone as 18041-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human pituitary tissue slide using 18041-1-AP (OXT antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 18041-1-PBS in a different storage buffer formulation.

  • IP experiment of mouse pituitary gland using 18041-1-AP (same clone as 18041-1-PBS)

    IP experiment of mouse pituitary gland using 18041-1-AP (same clone as 18041-1-PBS)

    IP result of anti-OXT (IP:18041-1-AP, 4ug; Detection:18041-1-AP 1:300) with mouse pituitary gland tissue lysate 1440 ug. This data was developed using the same antibody clone with 18041-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 18041-1-AP (same clone as 18041-1-PBS)

    IHC staining of mouse brain using 18041-1-AP (same clone as 18041-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 18041-1-AP (OXT antibody) at dilution of 1:800 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 18041-1-PBS in a different storage buffer formulation.

OXT Polyclonal antibody, PBS Only

OXT Polyclonal Antibody for IHC, IP, Indirect ELISA
Cat No. 18041-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

IHC, IP, Indirect ELISA

别名

Neurophysin 1, Ocytocin Neurophysin 1, Oxytocin, Oxytocin neurophysin 1, Oxytocin-neurophysin 1

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

18041-1-PBS targets OXT in IHC, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 IHC, IP, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag12672

Product name: Recombinant human OXT protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 19-125 aa of BC101841

Sequence: ACYIQNCPLGGKRAAPDLDVRKCLPCGPGGKGRCFGPNICCAEELGCFVGTAEALRCQEENYLPSPCQSGQKACGSGGRCAVLGLCCSPDGCHADPACDAEATFSQR

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 oxytocin, prepropeptide
别名 Neurophysin 1, Ocytocin Neurophysin 1, Oxytocin, Oxytocin neurophysin 1, Oxytocin-neurophysin 1
计算分子量 125 aa, 13 kDa
观测分子量13 kDa
GenBank蛋白编号BC101841
基因名称 OXT
Gene ID (NCBI) 5020
RRIDAB_2918056
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDP01178
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Oxytocin (OXT) is a neuropeptide involved in social-approach behaviors in humans and others mammals (PMID: 27325757). OXT is located on chromosome 20p13 and codes for a precursor protein that is synthetized to produce oxytocin and neurophysin I, and neurophysin I is the carrier protein for oxytocin (PMID: 1486803, PMID: 18566739). Oxytocin causes contraction of the smooth muscle of the uterus and of the mammary gland. Acts by binding to oxytocin receptor (OXTR) (PMID: 18174156).