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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
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Compatible Species
0
Conjugate
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验证数据展示

  • WB analysis of mouse spleen using 55405-1-AP (same clone as 55405-1-PBS)

    WB analysis of mouse spleen using 55405-1-AP (same clone as 55405-1-PBS)

    mouse spleen tissue were subjected to SDS PAGE followed by western blot with 55405-1-AP (NR4A3 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55405-1-PBS in a different storage buffer formulation.

  • WB analysis using 55405-1-AP (same clone as 55405-1-PBS)

    WB analysis using 55405-1-AP (same clone as 55405-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 55405-1-AP (NR4A3 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55405-1-PBS in a different storage buffer formulation.

  • IF Staining of ROS1728 using 55405-1-AP (same clone as 55405-1-PBS)

    IF Staining of ROS1728 using 55405-1-AP (same clone as 55405-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed ROS1728 cells using NR4A3 antibody (55405-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 55405-1-PBS in a different storage buffer formulation.

NR4A3 Polyclonal antibody, PBS Only

NR4A3 Polyclonal Antibody for WB, IF/ICC, Indirect ELISA
Cat No. 55405-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IF/ICC, Indirect ELISA

别名

TEC, NOR1, MINOR, CSMF, CHN

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

55405-1-PBS targets NR4A3 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IF/ICC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原 Peptide 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 nuclear receptor subfamily 4, group A, member 3
别名 TEC, NOR1, MINOR, CSMF, CHN
计算分子量 70 kDa
观测分子量 68 kDa
GenBank蛋白编号NM_006981
基因名称 NR4A3
Gene ID (NCBI) 8013
RRIDAB_2881322
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ92570
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Nuclear receptor 4A3 (NR4A3, also known as NOR-1), NR4A1 and NR4A2 are TFs belonging to NR4A orphan nuclear receptor subfamily. The role of all three NR4A members in regulating gene expression involved in cell proliferation, differentiation, apoptosis, inflammation and metabolism in cardiovascular diseases has been widely studied. In osteoblasts, NR4A receptor has been proved to regulate the expression and differentiation of osteoblast genes. It is reported that NR4A receptor is highly expressed in human coronary atherosclerotic lesions, and NR4A3 deficiency can reduce the proliferation and migration of VSMCs and the formation of neointima after vascular injury. Therefore, NR4A3 may play an important role in mediating phenotypic transformation of VSMC (PMID: 38629274). It is expected to be located in nucleus. The protein has three isforms, isoform alpha is highly expressed in skeletal muscle. Isoform beta is highly expressed in skeletal muscle and low expressed in fetal brain and placenta. The calculated molecular weight of NR4A3 is 68 kDa.