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Monochlorobimane

CAS号

76421-73-3

分子式

C10H11ClN2O2

主要靶点

仅限科研使用

Cat No : CM09609

Print datasheet

Synonyms

单氯二胺|mBBr|Monochlorobimane|Chlorobimane|Dye reagent

验证数据展示

  • CAS No.: 76421-73-3

    Monochlorobimane
    CAS#: 76421-73-3

产品信息

CAS号 76421-73-3
分子式 C10H11ClN2O2
主要靶点
主要通路
分子量 226.66
纯度 99%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
别名 单氯二胺|mBBr|Monochlorobimane|Chlorobimane|Dye reagent

体外活性

测量培养细胞中谷胱甘肽（GSH）的常用技术是向培养基中添加Monochlorobimane，其容易进入细胞并形成可通过荧光度量的GSH-Monochlorobimane加合物。Monochlorobimane方法与HPLC技术得到的结果具有可比性。Monochlorobimane浓度可降至25 mM，仍能准确测量均质物中的GSH含量。[1]

溶解度

DMSO:45.0 mg/mL (198.5 mM)

参考文献

1.Kamencic H, et al. Monochlorobimane fluorometric method to measure tissue glutathione. Anal Biochem. 2000 Nov 1;286(1):35-7.
2.Machado M D, et al. Assessment of cellular reduced glutathione content in Pseudokirchneriella subcapitata using monochlorobimane. Journal of applied phycology. 2012; 24: 1509-1516.
3.Hohwy M, et al. Novel prostaglandin D synthase inhibitors generated by fragment-based drug design. J Med Chem. 2008;51(7):2178-2186.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
=
×
×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
×
C1   V1   C2   V2