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Species Reactivity
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Conjugate
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验证数据展示

  • WB analysis of HEK-293 using 51094-1-AP (same clone as 51094-1-PBS)

    WB analysis of HEK-293 using 51094-1-AP (same clone as 51094-1-PBS)

    HEK-293 cells were subjected to SDS PAGE followed by western blot with 51094-1-AP (MEK6 antibody at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 51094-1-PBS in a different storage buffer formulation.

MEK6 Polyclonal antibody, PBS Only

MEK6 Polyclonal Antibody for WB, Indirect ELISA
Cat No. 51094-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, Indirect ELISA

别名

MAP2K6, MKK6, Dual specificity mitogen-activated protein kinase kinase 6, EC:2.7.12.2, MAP kinase kinase 6

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

51094-1-PBS targets MEK6 in WB, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human
免疫原

fusion protein

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 mitogen-activated protein kinase kinase 6
别名 MAP2K6, MKK6, Dual specificity mitogen-activated protein kinase kinase 6, EC:2.7.12.2, MAP kinase kinase 6
计算分子量 334 aa, 37 kDa
观测分子量 36 kDa
GenBank蛋白编号BC012009
基因名称 MEK6
Gene ID (NCBI) 5608
RRIDAB_2881246
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDP52564
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

MAPKK6 (Dual specificity mitogen activated protein kinase kinase 6), also known as MAP2K6 / MEK6 / MKK6, is a member of MAPKK protein kinase family. MKK6 plays an important role in intracellular signaling pathways leading toward activation of the p38 MAP kinase. MEK6 phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. MEK6 plays a complex role in cancer, with some evidence showing it can promote tumor growth. Overexpression of MEK6 has been linked to decreased survival in lung adenocarcinoma, breast cancer, and melanoma.