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Lumichrome

Lumichrome (7,8-Dimethylalloxazine) 是人类体内的内源性化合物，由核黄素光降解产生。它利用 p53 依赖机制抑制人肺癌细胞生长并诱导凋亡。

CAS号

1086-80-2

分子式

C12H10N4O2

主要靶点

Others

仅限科研使用

Cat No : CM11557

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Synonyms

7,8-Dimethylalloxazine|光色素

验证数据展示

  • CAS No.: 1086-80-2

    Lumichrome
    CAS#: 1086-80-2

产品信息

Lumichrome is a natural metabolite of riboflavin. Lumichrome produced by Rhizobium and other bacterial species induces major developmental changes in plants at nanomolar concentrations. Lumichrome can stimulate larval metamorphosis in ascidians and activate the LasR quorum sensing receptor of bacteria. Lumichrome competitively inhibits the uptake of riboflavin by riboflavin transporters from prokaryotes and eukaryotes.

CAS号 1086-80-2
分子式 C12H10N4O2
主要靶点 Others
主要通路 其他
分子量 242.23
纯度 99.65%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 7,8-Dimethylalloxazine|光色素

溶解度

DMSO:Soluble,H2O:Soluble

参考文献

1.Dakora FD, et al. Rhizosphere ecology of lumichrome and riboflavin, two bacterial signal molecules eliciting developmental changes in plants. Front Plant Sci. 2015 Sep 14;6:700.
2.Matiru VN, et al. The rhizosphere signal molecule lumichrome alters seedling development in both legumes and cereals. New Phytol. 2005 May;166(2):439-44.
3.Balcazar DE, et al. The superfamily keeps growing: Identification in trypanosomatids of RibJ, the first riboflavin transporter family in protists. PLoS Negl Trop Dis. 2017 Apr 13;11(4):e202005513.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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C1   V1   C2   V2