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Host
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Species Reactivity
0
Species Reactivity
0
Conjugate
0
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Compatible Species
0
Conjugate
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验证数据展示

  • WB analysis using 27543-1-AP (same clone as 27543-1-PBS)

    WB analysis using 27543-1-AP (same clone as 27543-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 27543-1-AP (Livin antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27543-1-PBS in a different storage buffer formulation.

  • IHC staining of human breast cancer using 27543-1-AP (same clone as 27543-1-PBS)

    IHC staining of human breast cancer using 27543-1-AP (same clone as 27543-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 27543-1-AP (Livin antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 27543-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with BIRC7 antibody included
  • IHC staining of human breast cancer using 27543-1-AP (same clone as 27543-1-PBS)

    IHC staining of human breast cancer using 27543-1-AP (same clone as 27543-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 27543-1-AP (Livin antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 27543-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with BIRC7 antibody included

Livin Polyclonal antibody, PBS Only

Livin Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 27543-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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Planning an IHC experiment? We recommend our IHCeasy BIRC7 Ready-To-Use IHC Kit. BIRC7 primary antibody included.

产品信息

27543-1-PBS targets Livin in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag26737

Product name: Recombinant human BIRC7 protein

Source: e coli.-derived, PET28a

Tag: 6*His

Domain: 1-216 aa of BC014475

Sequence: MGPKDSAKCLHRGPQPSHWAAGDGPTQERCGPRSLGSPVLGLDTCRAWDHVDGQILGQLRPLTEEEEEEGAGATLSRGPAFPGMGSEELRLASFYDWPLTAEVPPELLAAAGFFHTGHQDKVRCFFCYGGLQSWKRGDDPWTEHAKWFPSCQFLLRSKGRDFVHSVQETHSQLLGSWDPWEEPEDAAPVAPSVPASGYPELPTPRREVQSESAQEP

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 baculoviral IAP repeat-containing 7
别名
计算分子量 33 kDa
观测分子量 33 kDa
GenBank蛋白编号BC014475
基因名称 Livin
Gene ID (NCBI) 79444
RRIDAB_2880901
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ96CA5
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

BIRC7 also known as Livin, is one of the family members of the inhibitor of apoptosis protein (IAP). BIRC7 contains a BIR domain that has been shown to bind and inhibit caspases-3, −7 and −9, playing a key role in inhibiting apoptosis. Overexpression of BIRC7 in tumors has been linked with increased chemo- and radio-resistance, recurrence, and decreased patient survival. BIRC7 is closely associated with melanoma disease progression, apoptosis resistance, and chemotherapeutic drug resistance.

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