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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 29611-1-AP (same clone as 29611-1-PBS)

    WB analysis using 29611-1-AP (same clone as 29611-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 29611-1-AP (LAMTOR1 antibody) at dilution of 1:30000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29611-1-PBS in a different storage buffer formulation.

  • IF Staining of U-87 MG using 29611-1-AP (same clone as 29611-1-PBS)

    IF Staining of U-87 MG using 29611-1-AP (same clone as 29611-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed U-87 MG cells using LAMTOR1 antibody (29611-1-AP) at dilution of 1:200 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR002), CL594-phalloidin (red). This data was developed using the same antibody clone with 29611-1-PBS in a different storage buffer formulation.

LAMTOR1 Polyclonal antibody, PBS Only

LAMTOR1 Polyclonal Antibody for WB, IF/ICC, Indirect ELISA
Cat No. 29611-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IF/ICC, Indirect ELISA

别名

C11orf59, p27RF-Rho, p27RF Rho, p27Kip1-releasing factor from RhoA, Lipid raft adaptor protein p18

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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Planning an IHC experiment? We recommend our IHCeasy LAMTOR1 Ready-To-Use IHC Kit. LAMTOR1 primary antibody included.

产品信息

29611-1-PBS targets LAMTOR1 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IF/ICC, Indirect ELISA Application Description
经测试反应性 human
免疫原 LAMTOR1 fusion protein Ag31215 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 chromosome 11 open reading frame 59
别名 C11orf59, p27RF-Rho, p27RF Rho, p27Kip1-releasing factor from RhoA, Lipid raft adaptor protein p18
计算分子量 161 aa, 18 kDa
观测分子量 18 kDa
GenBank蛋白编号BC001706
基因名称 LAMTOR1
Gene ID (NCBI) 55004
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ6IAA8
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

LAMTOR1 (Late Endosome/Lysosome-Associated Membrane Protein 1) is a membrane protein specifically localized to the surface of late endosomes/lysosomes and is involved in lysosomal transport and maturation. LAMTOR1 is a key component of the lysosomal articulating protein complex Ragulator, which is required for the localization of the Ragulator complex to lysosomes. LAMTOR1 is a key component of the lysosomal bridging protein complex Ragulator and is required for the localization of the Ragulator complex to the lysosome. LAMTOR1 is involved in autophagy, cell growth, immune regulation, cancer development, and regulatory pathways of glucose metabolism. Recent studies have shown that in calorie restriction, lithocholic acid activates AMPK through the glucose-sensing pathway ( the lysosomal pathway ) and the body senses the metabolic signals induced by calorie restriction and exerts its role in slowing down the effects of aging and prolonging the lifespan, whereas deletion of LAMTOR1 results in the inability of AMPK to be activated in order to play its role.