验证数据展示
产品信息
31900-1-PBS targets KCNA6 in WB, Indirect ELISA applications and shows reactivity with human samples.
经测试应用 | WB, Indirect ELISA Application Description |
经测试反应性 | human |
免疫原 | KCNA6 fusion protein Ag35654 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | potassium voltage-gated channel, shaker-related subfamily, member 6 |
别名 | Protein Phosphatase 1, Regulatory Subunit 96, PPP1R96, Potassium voltage-gated channel subfamily A member 6, Kv1.6, Human Brain Potassium Channel-2 |
计算分子量 | 59 kDa,529aa |
观测分子量 | 65 kDa |
GenBank蛋白编号 | NM_002235.3 |
基因名称 | KCNA6 |
Gene ID (NCBI) | 3742 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity Purification |
UNIPROT ID | P17658 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
The Shaker-like Kv1 potassium channel family comprises 8 α subunits (Kv1.1-Kv1.8), which are key regulators of neuronal excitability in mammals (PMID: 7842011; 9581771; 22612818). Potassium voltage-gated channel subfamily A member 6 (KCNA6, also known as HBK2, Kv1.6, and PPP1R96) is a multi-pass membrane protein that is mainly expressed in the central and peripheral nervous system (PMID: 12042352; 8872310). The concentration of the Kv1.6 channel in the cell membrane can modulate the kinetic properties of Kv1.6-induced K+ current (PMID: 14575698).