验证数据展示
经过测试的应用
| Positive WB detected in | human plasma |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:500-1:3000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
24545-1-AP targets IGFALS in WB, ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 | IGFALS fusion protein Ag21696 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | insulin-like growth factor binding protein, acid labile subunit |
| 别名 | ALS, IGFALS |
| 计算分子量 | 605 aa, 66 kDa |
| 观测分子量 | 85 kDa |
| GenBank蛋白编号 | BC025681 |
| 基因名称 | IGFALS |
| Gene ID (NCBI) | 3483 |
| RRID | AB_3085738 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | P35858 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
THE ACID-LABILE SUBUNIT (ALS), a liver-derived, GH-dependent, 85-kD glycoprotein, is a key component of the 150-kD IGF circulating ternary complex(PMID: 17726072). The protein encoded by this gene is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this gene are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for IGFALS antibody 24545-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |