验证数据展示
产品信息
10066-2-PBS targets HINFP in WB, IF/ICC, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
经测试应用 | WB, IF/ICC, IP, Indirect ELISA Application Description |
经测试反应性 | human, mouse, rat |
免疫原 | HINFP fusion protein Ag0115 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | histone H4 transcription factor |
别名 | |
计算分子量 | 60 kDa |
观测分子量 | 60-70 kDa |
GenBank蛋白编号 | BC001073 |
基因名称 | HINFP |
Gene ID (NCBI) | 25988 |
RRID | AB_2117412 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | Q9BQA5 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Methylation of CpG dinucleotides is the major epigenetic modification in higher eukaryotic genomes. MIZF interacts with MBD2, a methyl-CpG-binding protein playing a critical role in DNA methylation-mediated transcriptional repression. MIZF functions as a negative regulator of transcription by binding to MBD2 and recruiting histone deacetylase (HDAC)-containing complexes. MIZF mRNA is present in various human tissues and cell lines and expressed as a 60kd protein.