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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 26739-1-AP (same clone as 26739-1-PBS)

    WB analysis using 26739-1-AP (same clone as 26739-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 26739-1-AP (GPBAR1 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 26739-1-PBS in a different storage buffer formulation.

GPBAR1 Polyclonal antibody, PBS Only

GPBAR1 Polyclonal Antibody for WB, Indirect ELISA
Cat No. 26739-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, Indirect ELISA

别名

BG37, GPCR, GPCR19, GPR131, G-protein coupled bile acid receptor 1

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

26739-1-PBS targets GPBAR1 in WB, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human
免疫原 GPBAR1 fusion protein Ag24893 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 G protein-coupled bile acid receptor 1
别名 BG37, GPCR, GPCR19, GPR131, G-protein coupled bile acid receptor 1
计算分子量 35 kDa
观测分子量32 kDa
GenBank蛋白编号BC033625
基因名称 GPBAR1
Gene ID (NCBI) 151306
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ8TDU6
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

GPBAR1 (G-protein coupled bile acid receptor 1), also known as TGR5 or M-BAR, is a cell-surface receptor for bile acid which belongs to the G-protein coupled receptor 1 family (20236244). GPBAR1 gene expression is widely distributed, including endocrine glands, adipocytes, muscles, immune organs, spinal cord, and the enteric nervous system (24411485, 20665558, 22521118). GPBAR1 activation has some important biological effects such as anti-inflammatory, energy homeostasis and metabolism, anti-apoptotic, and choleretic functions (24411485, 22521118). In addition, GPBAR1 is related to several diseases, such as Metabolic and cardiovascular disorders, Hepatic and pancreatic disorders, Inflammatory bowel diseases, Gastrointestinal cancer, and so on (24411485).