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验证数据展示

  • IHC staining of mouse ovary using 23138-1-AP (same clone as 23138-1-PBS)

    IHC staining of mouse ovary using 23138-1-AP (same clone as 23138-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse ovary tissue slide using 23138-1-AP (GLIS1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 23138-1-PBS in a different storage buffer formulation.

  • WB analysis of Jurkat using 23138-1-AP (same clone as 23138-1-PBS)

    WB analysis of Jurkat using 23138-1-AP (same clone as 23138-1-PBS)

    Jurkat cells were subjected to SDS PAGE followed by western blot with 23138-1-AP (GLIS1 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 23138-1-PBS in a different storage buffer formulation.

GLIS1 Polyclonal antibody, PBS Only

GLIS1 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 23138-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IHC, Indirect ELISA

别名

GLI similar 1, GLIS family zinc finger 1, GLI-similar 1, Zinc finger protein GLIS1

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

23138-1-PBS targets GLIS1 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

CatNo: Ag19214

Product name: Recombinant human GLIS1 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 360-620 aa of BC101799

Sequence: GPDTEADVLTECLVLQQLHTSTQLAASDGKGGCGLGQELLPGVYPGSITPHNGLASGLLPPAHDVPSRHHPLDATTSSHHHLSPLPMAESTRDGLGPGLLSPIVSPLKGLGPPPLPPSSQSHSPGGQPFPTLPSKPSYPPFQSPPPPPLPSPQGYQGSFHSIQSCFPYGDCYRMAEPAAGGDGLVGETHGFNPLRPNGYHSLSTPLPATGYEALAEASCPTALPQQPSEDVVSSGPEDCGFFPNGAFDHCLGHIPSIYTDT

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 GLIS family zinc finger 1
别名 GLI similar 1, GLIS family zinc finger 1, GLI-similar 1, Zinc finger protein GLIS1
计算分子量 620 aa, 66 kDa
观测分子量 66 kDa
GenBank蛋白编号BC101799
基因名称 GLIS1
Gene ID (NCBI) 148979
RRIDAB_2879216
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen Affinity purified
UNIPROT IDQ8NBF1
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

GLIS1 is a nuclear zinc finger transcription factor that integrates developmental signaling and transcriptional control during neural and epithelial differentiation. It enhances cellular reprogramming efficiency and modulates pathways linked to Hedgehog and Wnt signaling. Dysregulated GLIS1 expression contributes to cardiac malformations, cancer progression, and stemness reactivation, highlighting its dual role in developmental regulation and disease pathogenesis.

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