验证数据展示
产品信息
17164-1-PBS targets GBA2 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
经测试应用 | WB, Indirect ELISA Application Description |
经测试反应性 | human, mouse, rat |
免疫原 | GBA2 fusion protein Ag10606 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | glucosidase, beta (bile acid) 2 |
别名 | Bile acid beta-glucosidase GBA2, Beta-glucosidase 2, Beta-glucocerebrosidase 2, Beta glucosidase 2, Beta glucocerebrosidase 2 |
计算分子量 | 927 aa, 105 kDa |
观测分子量 | 105 kDa |
GenBank蛋白编号 | BC011363 |
基因名称 | GBA2 |
Gene ID (NCBI) | 57704 |
RRID | AB_2109077 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | Q9HCG7 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
GBA2(Non-lysosomal glucosylceramidase) is also named as KIAA1605,NLGase and belongs to the non-lysosomal glucosylceramidase family.It catalyzes the conversion of glucosylceramide to free glucose and ceramide and is involved in sphingomyelin generation and prevention of glycolipid accumulation.GBA2 contains a putative membrane-spanning domain and 2 potential N-glycosylation sites. However, glycosidase treatment indicated that GBA2 is not a glycoprotein(PMID:11489889).It has 3 isoforms produced by alternative splicing.