验证数据展示
产品信息
31553-1-PBS targets FYB in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.
经测试应用 | WB, IHC, Indirect ELISA Application Description |
经测试反应性 | human |
免疫原 | FYB fusion protein Ag35929 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | FYN binding protein (FYB-120/130) |
别名 | SLAP130, SLAP 130, p120/p130, FYB 120/130, ADAP |
计算分子量 | 85kDa,783aa |
观测分子量 | 110 kDa |
GenBank蛋白编号 | NM_199335.3 |
基因名称 | FYB |
Gene ID (NCBI) | 2533 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity Purification |
UNIPROT ID | O15117 |
储存缓冲液 | PBS only, pH 7.3. |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
FYN binding protein (FYB-120/130), also known as FYB, ADAP (Adhesion and degranulation-promoting adapter protein), and SLAP-130 (SLP-76-associated phosphoprotein) is a protein that is encoded by the FYB gene in humans. The protein is highly expressed in T cells, NK cells, bone marrow cells, and platelets, responsible for the signal transduction upon T cell receptor (TCR) stimulation with integrin activation.