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Host
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Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
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Compatible Species
0
Conjugate
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验证数据展示

  • WB analysis using 31553-1-AP (same clone as 31553-1-PBS)

    WB analysis using 31553-1-AP (same clone as 31553-1-PBS)

    Jurkat cells were subjected to SDS PAGE followed by western blot with 31553-1-AP (FYB antibody) at dilution of 1:2500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31553-1-PBS in a different storage buffer formulation.

  • IHC staining of human ovary cancer using 31553-1-AP (same clone as 31553-1-PBS)

    IHC staining of human ovary cancer using 31553-1-AP (same clone as 31553-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human ovary cancer tissue slide using 31553-1-AP (FYB antibody) at dilution of 1:500 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 31553-1-PBS in a different storage buffer formulation.

FYB Polyclonal antibody, PBS Only

FYB Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 31553-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, Indirect ELISA

别名

SLAP130, SLAP 130, p120/p130, FYB 120/130, ADAP

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

31553-1-PBS targets FYB in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag35929

Product name: Recombinant human FYB protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 600-783 aa of NM_199335.3

Sequence: EQDDISSHSQSGSGGIFPPPPDDDIYDGIEEEDADDGFPAPPKQLDMGDEVYDDVDTSDFPVSSAEMSQGTNVGKAKTEEKDLKKLKKQEKEEKDFRKKFKYDGEIRVLYSTKVTTSITSKKWGTRDLQVKPGESLEVIQTTDDTKVLCRNEEGKYGYVLRSYLADNDGEIYDDIADGCIYDND

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 FYN binding protein (FYB-120/130)
别名 SLAP130, SLAP 130, p120/p130, FYB 120/130, ADAP
计算分子量85kDa，783aa
观测分子量110 kDa
GenBank蛋白编号NM_199335.3
基因名称 FYB
Gene ID (NCBI) 2533
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity Purification
UNIPROT IDO15117
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

FYN binding protein (FYB-120/130), also known as FYB, ADAP (Adhesion and degranulation-promoting adapter protein), and SLAP-130 (SLP-76-associated phosphoprotein) is a protein that is encoded by the FYB gene in humans. The protein is highly expressed in T cells, NK cells, bone marrow cells, and platelets, responsible for the signal transduction upon T cell receptor (TCR) stimulation with integrin activation.