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验证数据展示

  • WB analysis of SGC-7901 using 28492-1-AP (same clone as 28492-1-PBS)

    WB analysis of SGC-7901 using 28492-1-AP (same clone as 28492-1-PBS)

    SGC-7901 cells were subjected to SDS PAGE followed by western blot with 28492-1-AP (filamin-c antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 28492-1-PBS in a different storage buffer formulation.

  • IHC staining of human colon using 28492-1-AP (same clone as 28492-1-PBS)

    IHC staining of human colon using 28492-1-AP (same clone as 28492-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon slide using 28492-1-AP (FLNC antibody) at dilution of 1:200 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28492-1-PBS in a different storage buffer formulation.

Filamin-C Polyclonal antibody, PBS Only

Filamin-C Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 28492-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, Indirect ELISA

别名

FLNC, FLN2, FilaminC, Filamin C, Filamin 2

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

28492-1-PBS targets Filamin-C in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human
免疫原 Filamin-C fusion protein Ag29328 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 filamin C, gamma (actin binding protein 280)
别名 FLNC, FLN2, FilaminC, Filamin C, Filamin 2
计算分子量 291 kDa
观测分子量 280-300 kDa
GenBank蛋白编号NM_001458
基因名称 FLNC
Gene ID (NCBI) 2318
RRIDAB_2918171
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ14315
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Filamin C (FLNC; also known as γ-FLN; ABP-L; FLN2), a muscle-specific filamin and a large actin-cross-linking protein. Human filamins are ~280 kDa homodimers, each monomer consisting of an N-terminal actin-binding domain followed by 24 immunoglobulin (Ig)-like domains (d1 to d24), the last of which mediates dimerization. FLNC is specifically expressed in cardiomyocytes and skeletal myocytes and is involved in the maintenance of structural integrity. High filamin C associated with better prognosis of prostate cancer, leukemia and breast cancer patients. ( PMID: 25577646, PMID: 30867563, PMID: 31131323)