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验证数据展示

  • WB analysis of human lung using 12092-1-AP (same clone as 12092-1-PBS)

    WB analysis of human lung using 12092-1-AP (same clone as 12092-1-PBS)

    human lung tissue were subjected to SDS PAGE followed by western blot with 12092-1-AP (FKBP7 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12092-1-PBS in a different storage buffer formulation.

  • IHC staining of human liver cancer using 12092-1-AP (same clone as 12092-1-PBS)

    IHC staining of human liver cancer using 12092-1-AP (same clone as 12092-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 12092-1-AP (FKBP7 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12092-1-PBS in a different storage buffer formulation.

  • IHC staining of human liver cancer using 12092-1-AP (same clone as 12092-1-PBS)

    IHC staining of human liver cancer using 12092-1-AP (same clone as 12092-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 12092-1-AP (FKBP7 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12092-1-PBS in a different storage buffer formulation.

FKBP7 Polyclonal antibody, PBS Only

FKBP7 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 12092-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, Indirect ELISA

别名

23 kDa FK506 binding protein, 23 kDa FK506-binding protein, 23 kDa FKBP, EC:5.2.1.8, FK506 binding protein 7

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

12092-1-PBS targets FKBP7 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag2733

Product name: Recombinant human FKBP7 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-222 aa of BC009711

Sequence: MPKTMHFLFRFIVFFYLWGLFTAQRQKKEESTEEVKIEVLHRPENCSKTSKKGDLLNAHYDGYLAKDGSKFYCSRTQNEGHPKWFVLGVGQVIKGLDIAMTDMCPGEKRKVVIPPSFAYGKEGYAEGKIPPDATLIFEIELYAVTKGPRSIETFKQIDMDNDRQLSKAEINLYLQREFEKDEKPRDKSYQDAVLEDIFKKNDHDGDGFISPKEYNVYQHDEL

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 FK506 binding protein 7
别名 23 kDa FK506 binding protein, 23 kDa FK506-binding protein, 23 kDa FKBP, EC:5.2.1.8, FK506 binding protein 7
计算分子量 259 aa, 30 kDa
观测分子量 30 kDa
GenBank蛋白编号BC009711
基因名称 FKBP7
Gene ID (NCBI) 51661
RRIDAB_2103418
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9Y680
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

FKBP7(FK506-binding protein 7) is also named as FKBP23 and belongs to immunophilin class of proteins family. This protein contains an N-terminal hydrophobic signal sequence, a PPIase motif, 2 EF-hand domains, and 2 putative N-glycosylation sites. The calculated molecular mass is about 25 kD, but becomes 33 kD following cleavage of the signal sequence(PMID:9806833). It could bind to BiP in ER in a process regulated by the concentration of Ca2+(PMID:22269648). It has 3 isoforms produced by alternative splicing.

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