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验证数据展示

  • WB analysis using 16253-1-AP (same clone as 16253-1-PBS)

    WB analysis using 16253-1-AP (same clone as 16253-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 16253-1-AP (EXO1 antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16253-1-PBS in a different storage buffer formulation.

  • IP experiment of mouse thymus using 16253-1-AP (same clone as 16253-1-PBS)

    IP experiment of mouse thymus using 16253-1-AP (same clone as 16253-1-PBS)

    IP result of anti-EXO1 (IP:16253-1-AP, 4ug; Detection:16253-1-AP 1:500) with mouse thymus tissue lysate 2800ug. This data was developed using the same antibody clone with 16253-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

EXO1 Polyclonal antibody, PBS Only

EXO1 Polyclonal Antibody for WB, IP, Indirect ELISA
Cat No. 16253-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IP, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

16253-1-PBS targets EXO1 in WB, IP, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IP, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原 EXO1 fusion protein Ag9253 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 exonuclease 1
别名
计算分子量 94 kDa
观测分子量 115-120 kDa
GenBank蛋白编号BC007491
基因名称 EXO1
Gene ID (NCBI) 9156
RRIDAB_2278140
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9UQ84
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

EXO1, also named as HEX1, is a 846 amino acid protein, which belongs to the XPG/RAD2 endonuclease family. EXO1 subfamily. EXO1 is highly expressed in bone marrow, testis and thymus and at lower levels in colon, lymph nodes, ovary, placenta, prostate, small intestine, spleen and stomach. EXO1 as 5'->3' double-stranded DNA exonuclease, which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. EXO1 functions in DNA mismatch repair (MMR) to excise mismatch-containing DNA tracts directed by strand breaks located either 5' or 3' to the mismatch. The calculated molecular weight of EXO1 is 94 kDa, but the modified EXO1 protein is about 115 kDa.