验证数据展示
产品信息
13182-1-PBS targets ETV6 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human, mouse, rat |
| 免疫原 |
CatNo: Ag3852 Product name: Recombinant human ETV6 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-355 aa of BC043399 Sequence: MSETPAQCSIKQERISYTPPESPVPSYASSTPLHVPVPRALRMEEDSIRLPAHLRLQPIYWSRDDVAQWLKWAENEFSLRPIDSNTFEMNGKALLLLTKEDFRYRSPHSGDVLYELLQHILKQRKPRILFSPFFHPGNSIHTQPEVILHQNHEEDNCVQRTPRPSVDNVHHNPPTIELLHRSRSPITTNHRPSPDPEQRPLRSPLDNMIRRLSPAERAQGPRPHQENNHQESYPLSVSPMENNHCPASSESHPKPSSPRQESTRVIQLMPSPIMHPLILNPRHSVDFKQSRLSEDGLHREGKPINLSHREDLAYMNHIMVSVSPPEEHAMPIGRIADCRLLWDYVYQLLSDSRYE 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | ets variant 6 |
| 别名 | |
| 计算分子量 | 452 aa, 53 kDa |
| 观测分子量 | 57-65 kDa |
| GenBank蛋白编号 | BC043399 |
| 基因名称 | ETV6 |
| Gene ID (NCBI) | 2120 |
| RRID | AB_2246688 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | P41212 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
ETV6, the E26 transformation-specific (ETS) family transcription repressor and tumor suppressor variant 6 gene, resides on chromosome 12p13, encodes a 57 kDa ETS family transcription factor with 3 highly conserved functional domains(PMID: 32841218). ETV6 is a well-studied hematopoietic transcription factor reported to play a key functional role in hematopoiesis, megakaryopoiesis, cell growth, and differentiation.
