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Host
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Species Reactivity
0
Species Reactivity
0
Conjugate
0
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0
Conjugate
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验证数据展示

  • WB analysis of mouse brain using 14518-1-AP (same clone as 14518-1-PBS)

    WB analysis of mouse brain using 14518-1-AP (same clone as 14518-1-PBS)

    mouse brain tissue were subjected to SDS PAGE followed by western blot with 14518-1-AP (ENSA antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14518-1-PBS in a different storage buffer formulation.

  • WB analysis using 14518-1-AP (same clone as 14518-1-PBS)

    WB analysis using 14518-1-AP (same clone as 14518-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 14518-1-AP (ENSA antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14518-1-PBS in a different storage buffer formulation.

  • IHC staining of human small intestine using 14518-1-AP (same clone as 14518-1-PBS)

    IHC staining of human small intestine using 14518-1-AP (same clone as 14518-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human small intestine tissue slide using 14518-1-AP (ENSA Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 14518-1-PBS in a different storage buffer formulation.

  • IHC staining of human colon using 14518-1-AP (same clone as 14518-1-PBS)

    IHC staining of human colon using 14518-1-AP (same clone as 14518-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 14518-1-AP (ENSA antibody) at dilution of 1:50 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14518-1-PBS in a different storage buffer formulation.

  • IHC staining of human colon using 14518-1-AP (same clone as 14518-1-PBS)

    IHC staining of human colon using 14518-1-AP (same clone as 14518-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 14518-1-AP (ENSA antibody) at dilution of 1:50 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14518-1-PBS in a different storage buffer formulation.

  • IF Staining of HeLa using 14518-1-AP (same clone as 14518-1-PBS)

    IF Staining of HeLa using 14518-1-AP (same clone as 14518-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed HeLa cells using ENSA antibody (14518-1-AP) at dilution of 1:400 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR002). This data was developed using the same antibody clone with 14518-1-PBS in a different storage buffer formulation.

ENSA Polyclonal antibody, PBS Only

ENSA Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA
Cat No. 14518-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IHC, IF/ICC, Indirect ELISA

别名

ARPP-19e, Alpha-endosulfine

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

14518-1-PBS targets ENSA in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IHC, IF/ICC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原 ENSA fusion protein Ag5982 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 endosulfine alpha
别名 ARPP-19e, Alpha-endosulfine
计算分子量 14 kDa
观测分子量 19 kDa
GenBank蛋白编号BC004461
基因名称 ENSA
Gene ID (NCBI) 2029
RRIDAB_10838808
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDO43768
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Endosulfine alpha (ENSA) belongs to the highly conserved c-AMP-regulated phosphoprotein (ARPP) family and was originally identified as an endogenous ligand for the sulfonylurea receptor, which regulates insulin secretion and glucose metabolism.ENSA not only regulates the cell cycle by interacting with microtubule-associated serine/threonine protein kinase-like (MASTL) enzymes, but also influences tumor growth through its own methylation. Recent studies have shown that ENSA is an important regulator of cholesterol biosynthesis in triple-negative breast cancer (TNBC) and that it triggers tumor growth by promoting cholesterol biosynthesis in TNBC.