验证数据展示
产品信息
28490-1-PBS targets DDIT4L in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.
经测试应用 | WB, IHC, Indirect ELISA Application Description |
经测试反应性 | human, mouse |
免疫原 | DDIT4L fusion protein Ag29616 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | DNA-damage-inducible transcript 4-like |
别名 | RTP801L, REDD-2, REDD2, HIF-1 responsive protein RTP801-like, DNA damage-inducible transcript 4-like protein |
计算分子量 | 193 aa, 22 kDa |
观测分子量 | 22 kDa |
GenBank蛋白编号 | BC013592 |
基因名称 | DDIT4L |
Gene ID (NCBI) | 115265 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | Q96D03 |
储存缓冲液 | PBS only, pH 7.3. |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
DNA-damage-inducible transcript 4-like protein(DDIT4L), encoded by the stress responsive gene REDD2, is a negative regulator of mTOR signaling, and expressed predominantly in skeletal muscle. It regulates the TOR signaling pathway upstream of the TSC1-TSC2 complex and downstream of AKT1. Also, DDIT4L involves in oxidized low-density lipoprotein-induced macrophage death sensitivity.