验证数据展示
产品信息
19070-1-PBS targets CREBZF in WB, Indirect ELISA applications and shows reactivity with mouse samples.
经测试应用 | WB, Indirect ELISA Application Description |
经测试反应性 | mouse |
免疫原 | CREBZF fusion protein Ag13625 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | CREB/ATF bZIP transcription factor |
别名 | |
计算分子量 | 272 aa, 30 kDa |
观测分子量 | 30 kDa |
GenBank蛋白编号 | BC093796 |
基因名称 | CREBZF |
Gene ID (NCBI) | 58487 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | Q9NS37 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
CREBZF is a basic region-leucine zipper (bZIP) transcription factor that belongs to the cAMP-response-element-binding protein (CREB)/activating transcription factor (ATF) family. CREBZF gene expression produces two isoforms, CREBZF-L (long isoform of CREBZF, also known as SMILE) and CREBZF-S (short isoform of CREBZF, also known as Zhangfei), resulting from alternative initiation codons. CREBZF fulfills its role in transcriptional regulation by heterodimerizing with other transcription factors as a coregulator and then binding to target promoters and regulating downstream gene expression. CREBZF has been identified as a novel transcriptional coregulator of a variety of nuclear receptors (PMID: 31124138).