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验证数据展示

  • WB analysis using 11416-1-AP (same clone as 11416-1-PBS)

    WB analysis using 11416-1-AP (same clone as 11416-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 11416-1-AP (COX7A2L antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11416-1-PBS in a different storage buffer formulation.

  • IHC staining of human ovary tumor using 11416-1-AP (same clone as 11416-1-PBS)

    IHC staining of human ovary tumor using 11416-1-AP (same clone as 11416-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human ovary tumor using 11416-1-AP (COX7A2L antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 11416-1-PBS in a different storage buffer formulation.

  • IHC staining of human ovary tumor using 11416-1-AP (same clone as 11416-1-PBS)

    IHC staining of human ovary tumor using 11416-1-AP (same clone as 11416-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human ovary tumor using 11416-1-AP (COX7A2L antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 11416-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

COX7A2L Polyclonal antibody, PBS Only

COX7A2L Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 11416-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

11416-1-PBS targets COX7A2L in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag1980

Product name: Recombinant human COX7A2L protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-114 aa of BC007095

Sequence: MYYKFSGFTQKLAGAWASEAYSPQGLKPVVSTEAPPIIFATPTKLTSDSTVYDYAGKNKVPELQKFFQKADGVPVYLKRGLPDQMLYRTTMALTVGGTIYCLIALYMASQPKNK

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 cytochrome c oxidase subunit VIIa polypeptide 2 like
别名
计算分子量 114 aa, 13 kDa
观测分子量 14 kDa
GenBank蛋白编号BC007095
基因名称 COX7A2L
Gene ID (NCBI) 9167
RRIDAB_2245402
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDO14548
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Cytochrome c oxidase (COX) is the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. The mitochondrially encoded subunits function in electron transfer, and the nuclear encoded subunits may function in the regulation and assembly of the complex. COX7A2L (cytochrome c oxidase subunit 7A-related protein), also known as COX7AR or COX7RP, is an inner mitochondrial membrane protein. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. Recently it was found that DNA methylation of COX7A2L had a significant association with therapy response in patients with breast cancer. In Alzheimer's disease the expression of COX7A2L was reduced.

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