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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
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0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 12661-1-AP (same clone as 12661-1-PBS)

    WB analysis using 12661-1-AP (same clone as 12661-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 12661-1-AP (COG8 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12661-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse testis using 12661-1-AP (same clone as 12661-1-PBS)

    IHC staining of mouse testis using 12661-1-AP (same clone as 12661-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 12661-1-AP (COG8 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12661-1-PBS in a different storage buffer formulation.

  • IHC staining of human ovary cancer using 12661-1-AP (same clone as 12661-1-PBS)

    IHC staining of human ovary cancer using 12661-1-AP (same clone as 12661-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human ovary cancer tissue slide using 12661-1-AP (COG8 antibody) at dilution of 1:200 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12661-1-PBS in a different storage buffer formulation.

  • IF Staining of A431 using 12661-1-AP (same clone as 12661-1-PBS)

    IF Staining of A431 using 12661-1-AP (same clone as 12661-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed A431 cells using COG8 antibody (12661-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (SA00013-2), CL594-phalloidin (red). This data was developed using the same antibody clone with 12661-1-PBS in a different storage buffer formulation.

COG8 Polyclonal antibody, PBS Only

COG8 Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA
Cat No. 12661-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, IF/ICC, Indirect ELISA

别名

COG complex subunit 8, DOR1

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

12661-1-PBS targets COG8 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, IF/ICC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 COG8 fusion protein Ag3341 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 component of oligomeric golgi complex 8
别名 COG complex subunit 8, DOR1
计算分子量 612 aa, 68 kDa
观测分子量 68 kDa
GenBank蛋白编号BC017492
基因名称 COG8
Gene ID (NCBI) 84342
RRIDAB_2244993
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ96MW5
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The conserved oligomeric Golgi (COG) complex is an eight subunit (COG1-8) peripheral Golgi membrane hetero-oligomeric protein complex. The COG complex is organized into lobes A (COG2-4) and B (COG5-7) with COG1 and COG8 bridging these lobes and is thought to play a critical role in vesicle tethering processes (PMID: 17331980). Cog8 localizes exclusively in the Golgi apparatus and is involved in the retrograde Golgi transport of resident proteins responsible for sugar chain (glycan) biosynthesis (PMID: 17220172).