验证数据展示
产品信息
31539-1-PBS targets COG4 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.
经测试应用 | WB, IHC, Indirect ELISA Application Description |
经测试反应性 | human, mouse |
免疫原 | COG4 fusion protein Ag35295 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | component of oligomeric golgi complex 4 |
别名 | COD1, COG complex subunit 4 |
计算分子量 | 89kDa,785aa |
观测分子量 | 89 kDa |
GenBank蛋白编号 | NM_001365426.1 |
基因名称 | COG4 |
Gene ID (NCBI) | 25839 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity Purification |
UNIPROT ID | Q9H9E3 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
COG complex subunit 4 is present in high molecular weight complexes that govern membrane movement between the Golgi and ER. Cog4 dependent trafficking and secretion of ECM components are required for protrusion and extension of the epithelial projections of the inner ear (PMID: 30287385). Loss-of-function COG4-mutant cells have impaired glycosylation and reduced COG4 protein levels (PMID: 30290151).