验证数据展示
产品信息
98576-2-PBS targets CD204 in FC applications and shows reactivity with mouse samples.
| 经测试应用 | FC Application Description |
| 经测试反应性 | mouse |
| 免疫原 |
CatNo: Eg4727 Product name: Recombinant Mouse MSR1 protein (rFc Tag) Source: mammalian cells-derived, pHZ-KIsec-N-rFc Tag: N-rFc Domain: 79-458 aa of NM_001113326.1 Sequence: QLLNWEMKNCLVCSLNTSDTSQGPMEKENTSKVEMRFTIIMEHMKDMEERIESISNSKADLIDTERFQNFSMATDQRLNDILLQLNSLISSVQEHGNSLDAISKSLQSLNMTLLDVQLHTETLNVRVRESTAKQQEDISKLEERVYKVSAEVQSVKEEQAHVEQEVKQEVRVLNNITNDLRLKDWEHSQTLKNITFIQGPPGPQGEKGDRGLTGQTGPPGAPGIRGIPGVKGDRGQIGFPGGRGNPGAPGKPGRSGSPGPKGQKGEKGSVGGSTPLKTVRLVGGSGAHEGRVEIFHQGQWGTICDDRWDIRAGQVVCRSLGYQEVLAVHKRAHFGQGTGPIWLNEVMCFGRESSIENCKINQWGVLSCSHSEDAGVTCTS 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | macrophage scavenger receptor 1 |
| 别名 | Macrophage acetylated LDL receptor I and II, macrophage scavenger receptor 1, Macrophage scavenger receptor types I and II, Msr1, Scavenger receptor type A |
| 计算分子量 | 50 kDa |
| GenBank蛋白编号 | NM_001113326.1 |
| 基因名称 | Msr1 |
| Gene ID (NCBI) | 20288 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | P30204-1 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
CD204, also known as MSR1, belongs to the scavenger receptor family, which is mainly expressed on the surface of macrophages. CD204 plays a key inflammatory role in various pathophysiological processes, including atherosclerosis, innate and adaptive immunity, lung and liver disease, and cancer. CD204 binds to a variety of ligands, including modified low-density lipoproteins (LDL) and lipids, and is involved in endocytosis, positive regulation of cholesterol storage, and positive regulation of macrophage-derived foam cell differentiation. Studies have shown that CD204 is significantly increased in peripheral blood mononuclear cells (PBMCs) from patients with asthma and chronic obstructive pulmonary disease (COPD), which may serve as a disease marker.
