验证数据展示
经过测试的应用
| Positive FC detected in | human monocyte-derived mature dendritic cells, MOLT-4 cells |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Flow Cytometry (FC) | FC : 0.25 ug per 10^6 cells in a 100 µl suspension |
| This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
98579-2-RR targets CD1b in FC applications and shows reactivity with human samples.
| 经测试应用 | FC Application Description |
| 经测试反应性 | human |
| 免疫原 |
Recombinant protein 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | CD1b molecule |
| 别名 | CD1, CD1b molecule, R1 |
| 计算分子量 | 333 aa, 37 kDa |
| GenBank蛋白编号 | BC069481 |
| 基因名称 | CD1B |
| Gene ID (NCBI) | 910 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | P29016 |
| 储存缓冲液 | PBS with 0.09% sodium azide, pH 7.3. |
| 储存条件 | Store at 2 - 8°C. Stable for one year after shipment. |
背景介绍
CD1b is a ~45 kDa transmembrane glycoprotein that belongs to the MHC class I-like CD1 family. It associates non-covalently with β2-microglobulin to form a functional antigen-presenting heterodimer. CD1b is expressed on cortical thymocytes, dendritic cells (PMID: 17593659). It has the capacity to bind self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on T cells (PMID: 30399491).
实验方案
| Product Specific Protocols | |
|---|---|
| FC protocol for CD1b antibody 98579-2-RR | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
