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验证数据展示

  • WB analysis using 26933-1-AP (same clone as 26933-1-PBS)

    WB analysis using 26933-1-AP (same clone as 26933-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 26933-1-AP (CCNK antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 26933-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 26933-1-AP (same clone as 26933-1-PBS)

    IHC staining of mouse brain using 26933-1-AP (same clone as 26933-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 26933-1-AP (CCNK antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 26933-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with CCNK antibody included

CCNK Polyclonal antibody, PBS Only

CCNK Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 26933-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, Indirect ELISA

别名

Cyclin K, CPR4, Cyclin-K

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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Planning an IHC experiment? We recommend our IHCeasy CCNK Ready-To-Use IHC Kit. CCNK primary antibody included.

产品信息

26933-1-PBS targets CCNK in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag25556

Product name: Recombinant human CCNK protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-354 aa of BC015935

Sequence: MKENKENSSPSVTSANLDHTKPCWYWDKKDLAHTPSQLEGLDPATEARYRREGARFIFDVGTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETPKKCKDIIKTARSLLNDVQFGQFGDDPKEEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQKLVQMAWTFVNDSLCTTLSLQWEPEIIAVAVMYLAGRLCKFEIQEWTSKPMYRRWWEQFVQDVPVDVLEDICHQILDLYSQGKQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPLILLQGWACRQPATHLLPSPLEDSLLCPRPFPHPACLQLGGWGGQPG

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 cyclin K
别名 Cyclin K, CPR4, Cyclin-K
计算分子量 64 kDa
观测分子量 70 kDa
GenBank蛋白编号BC015935
基因名称 CCNK
Gene ID (NCBI) 8812
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDO75909
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Cyclin-K (CCNK) is also named as CPR4 and belongs to the cyclin family. CCNK is a regulatory subunit of cyclin-dependent kinases that mediates activation of target kinases (PMID:10574912). It plays a role in transcriptional regulation via its role in regulating the phosphorylation of the C-terminal domain (CTD) of the large subunit of RNA polymerase II (POLR2A) (PMID:9632813). The Cyclin K/Cdk12 complex maintains genomic stability via regulation of expression of DNA damage response genes (PMID:22012619).

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