验证数据展示
产品信息
17239-1-PBS targets Complement C6 in WB, IHC, IP, Indirect ELISA applications and shows reactivity with human, mouse samples.
经测试应用 | WB, IHC, IP, Indirect ELISA Application Description |
经测试反应性 | human, mouse |
免疫原 | Complement C6 fusion protein Ag11083 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | complement component 6 |
别名 | C6, Complement component C6, complement component 6 |
计算分子量 | 934 aa, 105 kDa |
观测分子量 | 105 kDa |
GenBank蛋白编号 | BC035723 |
基因名称 | C6 |
Gene ID (NCBI) | 729 |
RRID | AB_2878366 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | P13671 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
The final consequence of complement activation is formation of the membrane attack complex (MAC), a multiprotein assembly that perforates cell membranes, forming transmembrane channels. C6 is 1 of 5 late-acting proteins of complement that participate in assembly and function of the MAC. The deduced C6 protein contains 934 amino acids, including a 21-amino acid N-terminal signal sequence and 2 N-glycosylation sites. Mutations in the C6 gene are associated with complement component-6 deficiency.