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验证数据展示

  • WB analysis using 26696-1-AP (same clone as 26696-1-PBS)

    WB analysis using 26696-1-AP (same clone as 26696-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 26696-1-AP (BMPR1B antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 26696-1-PBS in a different storage buffer formulation.

  • IHC staining of rat ovary using 26696-1-AP (same clone as 26696-1-PBS)

    IHC staining of rat ovary using 26696-1-AP (same clone as 26696-1-PBS)

    Immunohistochemical analysis of paraffin-embedded rat ovary tissue slide using 26696-1-AP (BMPR1B antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 26696-1-PBS in a different storage buffer formulation.

  • IHC staining of rat ovary using 26696-1-AP (same clone as 26696-1-PBS)

    IHC staining of rat ovary using 26696-1-AP (same clone as 26696-1-PBS)

    Immunohistochemical analysis of paraffin-embedded rat ovary tissue slide using 26696-1-AP (BMPR1B antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 26696-1-PBS in a different storage buffer formulation.

  • IF Staining of MCF-7 using 26696-1-AP (same clone as 26696-1-PBS)

    IF Staining of MCF-7 using 26696-1-AP (same clone as 26696-1-PBS)

    Immunofluorescent analysis of (-20°C Methanol) fixed MCF-7 cells using BMPR1B antibody (26696-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 26696-1-PBS in a different storage buffer formulation.

BMPR1B Polyclonal antibody, PBS Only

BMPR1B Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA
Cat No. 26696-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, IF/ICC, Indirect ELISA

别名

BMP type 1B receptor, BMP type-1B receptor, BMPR 1B, BMPR-1B, Bone morphogenetic protein receptor type-1B

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

26696-1-PBS targets BMPR1B in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, IF/ICC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag24902

Product name: Recombinant human BMPR1B protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 16-57 aa of BC047773

Sequence: EDGESTAPTPRPKVLRCKCHHHCPEDSVNNICSTDGYCFTMI

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 bone morphogenetic protein receptor, type IB
别名 BMP type 1B receptor, BMP type-1B receptor, BMPR 1B, BMPR-1B, Bone morphogenetic protein receptor type-1B
计算分子量 57 kDa
观测分子量 50 kDa
GenBank蛋白编号BC047773
基因名称 BMPR1B
Gene ID (NCBI) 658
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDO00238
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

BMPR1B (Bone morphogenetic protein receptor type-1B) is also named as CDw293. BMPR1B belongs to the protein kinase superfamily. BMPR1B is on ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. BMPR1B is receptor for BMP7/OP-1 and GDF5. BMPR1B Positively regulates chondrocyte differentiation through GDF5 interaction.

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