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验证数据展示

  • IHC staining of mouse brain using 30046-1-AP (same clone as 30046-1-PBS)

    IHC staining of mouse brain using 30046-1-AP (same clone as 30046-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 30046-1-AP (BAHCC1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30046-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 30046-1-AP (same clone as 30046-1-PBS)

    IHC staining of mouse brain using 30046-1-AP (same clone as 30046-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 30046-1-AP (BAHCC1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30046-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 30046-1-AP (same clone as 30046-1-PBS)

    IHC staining of mouse brain using 30046-1-AP (same clone as 30046-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 30046-1-AP (BAHCC1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30046-1-PBS in a different storage buffer formulation.

  • IHC staining of rat brain using 30046-1-AP (same clone as 30046-1-PBS)

    IHC staining of rat brain using 30046-1-AP (same clone as 30046-1-PBS)

    Immunohistochemical analysis of paraffin-embedded rat brain tissue slide using 30046-1-AP (BAHCC1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30046-1-PBS in a different storage buffer formulation.

  • IHC staining of rat brain using 30046-1-AP (same clone as 30046-1-PBS)

    IHC staining of rat brain using 30046-1-AP (same clone as 30046-1-PBS)

    Immunohistochemical analysis of paraffin-embedded rat brain tissue slide using 30046-1-AP (BAHCC1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30046-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse colon using 30046-1-AP (same clone as 30046-1-PBS)

    IHC staining of mouse colon using 30046-1-AP (same clone as 30046-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse colon tissue slide using 30046-1-AP (BAHCC1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30046-1-PBS in a different storage buffer formulation.

  • IF Staining of A549 using 30046-1-AP (same clone as 30046-1-PBS)

    IF Staining of A549 using 30046-1-AP (same clone as 30046-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed A549 cells using BAHCC1 antibody (30046-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L), CL594-phalloidin (red). This data was developed using the same antibody clone with 30046-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 30046-1-AP (same clone as 30046-1-PBS)

    IHC staining of mouse brain using 30046-1-AP (same clone as 30046-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 30046-1-AP (BAHCC1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30046-1-PBS in a different storage buffer formulation.

BAHCC1 Polyclonal antibody, PBS Only

BAHCC1 Polyclonal Antibody for IHC, IF/ICC, Indirect ELISA
Cat No. 30046-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

IHC, IF/ICC, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

30046-1-PBS targets BAHCC1 in IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 IHC, IF/ICC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 BAHCC1 fusion protein Ag32599 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 BAH domain and coiled-coil containing 1
别名
计算分子量280 kDa
观测分子量 280 kDa
GenBank蛋白编号NM_001291324.1
基因名称 BAHCC1
Gene ID (NCBI) 57597
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9P281
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

BAHCC1 (BAH and coiled-coil domain-containing protein 1) is also named as BAHD2, KIAA1447 and BAH domain-containing protein 2. BAHCC1 is a transcriptional regulator controlling expression of E2F/KLF-dependent cell-cycle and DNA-repair genes. BAHCC1 associates with BRG1-containing remodeling complexes at the promoters of these genes. BAHCC1 silencing leads to decreased cell proliferation and delayed DNA repair. Consequently, BAHCC1 deficiency cooperates with PARP inhibition to induce melanoma cell death (PMID: 37924516). depletion of BAHCC1, or disruption of the BAHCC1BAH-H3K27me3 interaction, causes derepression of H3K27me3-targeted genes that are involved in tumor suppression and cell differentiation, leading to suppression of oncogenesis (PMID: 33139953).