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验证数据展示

  • WB analysis of Daudi using 27635-1-AP (same clone as 27635-1-PBS)

    WB analysis of Daudi using 27635-1-AP (same clone as 27635-1-PBS)

    Daudi cells were subjected to SDS PAGE followed by western blot with 27635-1-AP (BACH2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27635-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

BACH2 Polyclonal antibody, PBS Only

BACH2 Polyclonal Antibody for WB, Indirect ELISA
Cat No. 27635-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

27635-1-PBS targets BACH2 in WB, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human
免疫原 BACH2 fusion protein Ag26526 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 BTB and CNC homology 1, basic leucine zipper transcription factor 2
别名
计算分子量 93 kDa
观测分子量 120-130 kDa
GenBank蛋白编号NM_001170794
基因名称 BACH2
Gene ID (NCBI) 60468
RRIDAB_2880934
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

BACH2, also named as Transcription regulator protein BACH2, is a 841 amino acid protein, which is widely expressed within the B-lymphoid lineage, except in plasma cells. BACH2 contains an N-terminal BTB domain involved in its transcriptional function, but instead of having zinc fingers at the C-terminus, it binds to DNA through a basic leucine zipper motif. BACH2 binds DNA consensus sequences, termed MARE motifs, by forming a heterodimer with small leucine zipper MAF proteins such as MAFK, MAFG, and MAFF. The calculated molecular weight of BACH2 is 92 kDa, but the post-modifiction of BACH2 is about 120-130 kDa. (PMID: 24277074 )