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验证数据展示

  • IHC staining of mouse kidney using 26834-1-AP (same clone as 26834-1-PBS)

    IHC staining of mouse kidney using 26834-1-AP (same clone as 26834-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 26834-1-AP (ACMSD antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 26834-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse kidney using 26834-1-AP (same clone as 26834-1-PBS)

    IHC staining of mouse kidney using 26834-1-AP (same clone as 26834-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 26834-1-AP (ACMSD antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 26834-1-PBS in a different storage buffer formulation.

ACMSD Polyclonal antibody, PBS Only

ACMSD Polyclonal Antibody for IHC, Indirect ELISA
Cat No. 26834-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

IHC, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

26834-1-PBS targets ACMSD in IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 IHC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原 ACMSD fusion protein Ag25230 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 aminocarboxymuconate semialdehyde decarboxylase
别名
计算分子量 38 kDa
GenBank蛋白编号BC016018
基因名称 ACMSD
Gene ID (NCBI) 130013
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ8TDX5
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

ACMSD (alpha-amino-beta-carboxy-muconate-semialdehyde decarboxylase ) is the key enzyme that regulates the de novo NAD+ synthesis from tryptophan. ACMSD is highly expressed in the liver, kidney and to a lower degree in brain under physiological conditions. The enzyme is primarily cytosolic and is positioned at a critical branching point in the kynurenine pathway, wherein it influences the fate of the precursor 2-amino-3-carboxymuconic-6-semialdehyde (ACMS).