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Host
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Species Reactivity
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验证数据展示

  • FC experiment of human PBMCs using 98097-1-RR (same clone as 98097-1-PBS)

    FC experiment of human PBMCs using 98097-1-RR (same clone as 98097-1-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human ICAM3/CD50 Rabbit Recombinant Antibody (98097-1-RR, Clone:241418E8) or Isotype Control and PE-conjugated Goat Anti-Rabbit IgG. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98097-1-PBS in a different storage buffer formulation.

  • FC experiment of human PBMCs using 98097-1-RR (same clone as 98097-1-PBS)

    FC experiment of human PBMCs using 98097-1-RR (same clone as 98097-1-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human ICAM3/CD50 Rabbit Recombinant Antibody (98097-1-RR, Clone:241418E8) or Isotype Control and PE-conjugated Goat Anti-Rabbit IgG. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98097-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98097-1-RR

    Affinity and Kinetic Characterization of 98097-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98097-1-RR against Human ICAM3/CD50 were performed. The affinity constant is 0.366 nM.

Anti-Human ICAM3/CD50 Rabbit Recombinant Antibody, PBS Only

ICAM3/CD50 Uni-rAbTM Recombinant Antibody for FC, Indirect ELISA
Cat No. 98097-1-PBS

产品说明书

CloneNo. 241418E8

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC, Indirect ELISA

别名

CDW50, ICAM3, 241418E8, CD50, ICAM 3

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

98097-1-PBS targets ICAM3/CD50 in FC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 FC, Indirect ELISA Application Description
经测试反应性 human
免疫原 Recombinant Protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 intercellular adhesion molecule 3
别名 CDW50, ICAM3, 241418E8, CD50, ICAM 3
计算分子量 547 aa, 60 kDa
GenBank蛋白编号BC058903
基因名称 ICAM3/CD50
Gene ID (NCBI) 3385
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDP32942
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The intercellular adhesion molecule (ICAM) family is a subfamily of immunoglobulin superfamily with five known ICAM family members (ICAM1 to ICAM5) which play a role in inflammation, immune responses, and intracellular signaling (PMID: 23287428; 29477378). ICAM3, also known as CD50, is a type I transmembrane glycoprotein that contains five C2-type immunoglobulin-like domains in its extracellular region, a single transmembrane segment, and a C-terminus cytoplasmic tail. ICAM3 is selectively expressed on leukocytes (PMID: 1730916; 8132828). It is the primary ligand for LFA-1 and is involved in various immune processes, including T-cell activation, and macrophage recognition of apoptotic cells (PMID: 11812993; 23775590).