• HEK293 expressed
  • Endotoxin-free
  • Animal-component free

HumanKine® recombinant human IL-17 (IL-17A) protein


0.24-1.2 ng/mL EC50

Species Reactivity




Cat No : HZ-1113

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CTLA 8, CTLA8, IL 17, IL 17A, IL17, IL-17, IL17A, IL-17A, interleukin 17A

Technical Specifications

GeneID 3605
Species Human
Expression HEK293
Activity 0.24-1.2 ng/mL EC50
Purity >95%
Endotoxin<1 EU/µg
Accession NumberQ16552
Molecular Mass 30 to 35 kDa, homodimer
Formulation 10 mM Tris-HCl pH 7.4+ 250 mM NaCl, See Certificate of Analysis for details
Species Reactivity human

Stability and Reconstitution

Stability and Storage Lyophilized proteins are stable for 1 year from the date of receipt if stored between (-20°C) and (-80°C). Upon reconstitution we recommend that the solution can be stored at (4°C) for short term or at (-20°C) to (-80°C) for long term. Repeated freeze thaw cycles should be avoided with reconstituted products.
Reconstitution Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile 1xPBS pH 7.4 containing 0.1% endotoxin-free recombinant human serum albumin (HSA).


IL-17 (IL-17A) is a homodimeric glycoprotein with an apparent molecular mass of 30 to 35 kDa. The IL-17 family is comprised of at least 6 proinflammatory cytokines that share a conserved cystine-knot structure but diverge at the N-terminus. IL-17 family members are glycoproteins that induce local cytokine production and recruit granulocytes to sites of inflammation (PMID: 15485625; 11574464).


CTLA 8, CTLA8, IL 17, IL 17A, IL17, IL-17, IL17A, IL-17A, interleukin 17A




IL-17 induces antitumor immunity by promoting beneficial neutrophil recruitment and activation in esophageal squamous cell carcinoma.

Authors - Chang-Long Chen

J Invest Dermatol

Chrna5 is overexpressed in psoriasis patients and promotes psoriasis-like inflammation in mouse models.

Authors - Jing Wang

Arthritis Rheumatol

Thymidine phosphorylase regulates the expression of CXCL10 in rheumatoid arthritis fibroblast-like synoviocytes.

Authors - YukoToyoda

Front Immunol

Therapeutic Effects of (5R)-5-Hydroxytriptolide on Fibroblast-Like Synoviocytes in Rheumatoid Arthritis via lncRNA WAKMAR2/miR-4478/E2F1/p53 Axis.

Authors - Xinpeng Zhou

PLoS One

Isolation of All CD44 Transcripts in Human Epidermis and Regulation of Their Expression by Various Agents.

Authors - KwesiTeye

Acta Otolaryngol

Multiplex analyses of cytokine and chemokine release from the cultured fibroblast of nasal polyps: the effect of IL-17A.

Authors - HirotomoHomma