ZAK Monoclonal antibody
ZAK Monoclonal Antibody for WB, ELISA
Host / Isotype
Mouse / IgG2a
Reactivity
Human, rat, rabbit
Applications
WB, ELISA
Conjugate
Unconjugated
CloneNo.
2H10E4
验证数据展示
经过测试的应用
| Positive WB detected in | U2OS cells, rat skeletal muscle tissue, rabbit skeletal muscle tissue, Saos-2 cells, HeLa cells, HEK-293 cells, Jurkat cells, K-562 cells |
推荐稀释比
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:5000-1:50000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
68599-1-Ig targets ZAK in WB, ELISA applications and shows reactivity with Human, rat, rabbit samples.
| Tested Applications | WB, ELISA |
| Tested Reactivity | Human, rat, rabbit |
| Immunogen | ZAK fusion protein Ag6747 种属同源性预测 |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | sterile alpha motif and leucine zipper containing kinase AZK |
| Synonyms | AZK, HCCS 4, MLK related kinase, MLK7, mlklak, MLT, MLTK, MRK, ZAK |
| Calculated Molecular Weight | 91 kDa |
| Observed Molecular Weight | 91 kDa |
| GenBank Accession Number | BC001401 |
| Gene Symbol | ZAK |
| Gene ID (NCBI) | 51776 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | Q9NYL2 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
ZAK(sterile-alpha motif and leucine zipper containing kinase AZK) is also named as MLTK, MAPKKK, mlklak, MLK7, AZK, MLT, MRK, HCCS-4 and belongs to the MAPKKK family. It is a mitogen-activated protein kinase kinase kinase (MAP3K) that activates the stress-activated protein kinase/c-jun N-terminal kinase pathway and activates NF-kappaB. ZAK contributes to regulation of DNA damage checkpoints through a p38gamma-independent pathway. This protein has 3 isoforms produced by alternative splicing with the MW of 91 kDa, 51 kDa and 35 kDa.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for ZAK antibody 68599-1-Ig | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
