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Retinyl acetate

CAS号

127-47-9

分子式

C22H32O2

主要靶点

仅限科研使用

Cat No : CM00569

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Synonyms

视黄醇乙酸酯|视黄醇乙酸酯(维生素A醋酸酯)|VA|Vitamin A|Vitamin A acetate|Vitamin A Acetate|inhibit|Inhibitor|Retinol|Retinol acetate|Retinol Acetate|Retinyl acetate|Retinyl Acetate|Retinyl (Retinol) Acetate|Retinyl

验证数据展示

  • CAS No.: 127-47-9

    Retinyl acetate
    CAS#: 127-47-9

产品信息

CAS号 127-47-9
分子式 C22H32O2
主要靶点
主要通路 代谢
分子量 328.49
纯度 ≥98%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
别名 视黄醇乙酸酯|视黄醇乙酸酯(维生素A醋酸酯)|VA|Vitamin A|Vitamin A acetate|Vitamin A Acetate|inhibit|Inhibitor|Retinol|Retinol acetate|Retinol Acetate|Retinyl acetate|Retinyl Acetate|Retinyl (Retinol) Acetate|Retinyl

体内活性

Retinyl acetate （VAA）（在其它常规饮食基础上补充）对105个半同种异体细胞（亚最佳剂量）在小鼠的宿主抗嫁接（HvG）反应中有应答，而常规饮食能的小鼠则无此现象。[2] Retinyl acetate 能终止通过在新生CBA小鼠体内静脉注射（CBA X C57BL/10ScSn）F1杂交种淋巴细胞而诱发的稳固且持久的耐受状态，其效果是增加产生IL-2的T细胞群体的比例。[3] 补充Retinyl acetate 的饮食使得高剂量Mycobacterium bovis感染的小鼠对分枝杆菌纯化蛋白衍生物的皮肤反应呈阳性，并且它们的脾细胞在体外显示出增加的IL-2产生。[4]

体外活性

Retinyl acetate （VAA）（在其它常规饮食基础上补充）对105个半同种异体细胞（亚最佳剂量）在小鼠的宿主抗嫁接（HvG）反应中有应答，而常规饮食能的小鼠则无此现象。[2] Retinyl acetate 能终止通过在新生CBA小鼠体内静脉注射（CBA X C57BL/10ScSn）F1杂交种淋巴细胞而诱发的稳固且持久的耐受状态，其效果是增加产生IL-2的T细胞群体的比例。[3] 补充Retinyl acetate 的饮食使得高剂量Mycobacterium bovis感染的小鼠对分枝杆菌纯化蛋白衍生物的皮肤反应呈阳性，并且它们的脾细胞在体外显示出增加的IL-2产生。[4]

溶解度

DMSO:40 mg/mL (121.77 mM);Ethanol:60 mg/mL (182.6 mM);H2O:< 1 mg/mL (insoluble or slightly soluble)

参考文献

1.Stephensen CB, et al. Annu Rev Nutr, 2001, 21, 167-192.
2.Malkovsky M, et al. Nature, 1983 Mar, 302(5906), 338-340.
3.Malkovsky M, et al. Proc Natl Acad Sci U S A, 1985, 82(2), 536-538.
4.Colizzi V, et al. Infect Immun, 1985, 48(2), 581-583.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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