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VIP(6-28)(human, rat, porcine, bovine) acetate

CAS号

分子式

C128H211N37O36S

主要靶点

Others

仅限科研使用

Cat No : CM20644

Print datasheet

Synonyms

VIP(628)(human, rat, porcine, bovine) acetate|VIP Acetate|VIP receptor|VIP(6 28)(human, rat, porcine, bovine) acetate

验证数据展示

  • CAS No.:

    VIP(6-28)(human, rat, porcine, bovine) acetate
    CAS#:

产品信息

CAS号
分子式 C128H211N37O36S
主要靶点 Others
主要通路 其他
分子量 2876.34
纯度 99.29%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
别名 VIP(628)(human, rat, porcine, bovine) acetate|VIP Acetate|VIP receptor|VIP(6 28)(human, rat, porcine, bovine) acetate

体外活性

VIP(6-28)(human, rat, porcine, bovine) acetate（10、30或100 μM）通过分别降低52%、64%或81%来减少10 μM VIP刺激后cAMP水平的增加。在富含神经元和非神经元的分离培养细胞中，对VIP(6-28)(human, rat, porcine, bovine) acetate阻断VIP刺激下cAMP水平增加的能力获得了类似结果。在测试的任何浓度下，VIP(6-28)(human, rat, porcine, bovine) acetate本身不改变cAMP水平。与其通过64%降低VIP刺激下cAMP水平提升的能力相比，向培养基中添加30 μM VIP(6-28)(human, rat, porcine, bovine) acetate后，在用异丙肾上腺素或福斯可林（每种10 μM）刺激成年神经节后测得的cAMP水平并没有显著改变。

参考文献

1.Mohney RP, et al. Vasoactive intestinal peptide enhances its own expression in sympathetic neurons after injury. J Neurosci. 1998 Jul 15;18(14):5285-93.

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