• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

Tubulin inhibitor 6

Tubulin inhibitor 6 (iHAP1) 是一种微管蛋白抑制剂，抑制微管蛋白聚合，IC50为 0.87 μM。它抑制多种癌细胞系，抑制 K562 细胞生长，IC50为 840 nM。

CAS号

105925-39-1

分子式

C20H14ClNO2S

主要靶点

Microtubule Associated

仅限科研使用

Cat No : CM05107

Print datasheet

Synonyms

iHAP1

验证数据展示

  • CAS No.: 105925-39-1

    Tubulin inhibitor 6
    CAS#: 105925-39-1

产品信息

Tubulin inhibitor 6 is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines.

CAS号 105925-39-1
分子式 C20H14ClNO2S
主要靶点 Microtubule Associated
主要通路 细胞骨架
分子量 367.85
纯度 99.53%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 iHAP1

靶点活性

tubulin polymerization:0.87 μM (IC50)

体外活性

Tubulin inhibitor 6 exhibits submicromolar antiproliferative activity.

溶解度

DMSO:59.5 mg/mL (161.75mM),Sonification is recommended.

参考文献

1.Prinz H, et al. N-benzoylated phenoxazines and phenothiazines: synthesis, antiproliferative activity, and inhibition of tubulin polymerization. J Med Chem. 2011 Jun 23;54(12):4247-63.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
=
×
×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
×
C1   V1   C2   V2