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Tripelennamine hydrochloride

CAS号

154-69-8

分子式

C16H21N3·HCl

主要靶点

Histamine Receptor

仅限科研使用

Cat No : CM00618

Print datasheet

Synonyms

antihistaminic|allergic response|Endogenous Metabolite|conjunctivitis|inhibit|H1 receptor|Histamine Receptor|HistamineReceptor|Inhibitor|rhinitis|Pyribenzamine HCl|Pyribenzamine hydrochloride|Pyribenzamine Hydrochloride|Tripelennamine|Tripelennamine HCl|Tripelennamine hydrochloride|Tripelennamine Hydrochloride|去敏灵|盐酸曲吡那敏

验证数据展示

  • CAS No.: 154-69-8

    Tripelennamine hydrochloride
    CAS#: 154-69-8

产品信息

CAS号 154-69-8
分子式 C16H21N3·HCl
主要靶点 Histamine Receptor
主要通路 G 蛋白偶联受体|神经科学|免疫与炎症
分子量 291.82
纯度 100%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
别名 antihistaminic|allergic response|Endogenous Metabolite|conjunctivitis|inhibit|H1 receptor|Histamine Receptor|HistamineReceptor|Inhibitor|rhinitis|Pyribenzamine HCl|Pyribenzamine hydrochloride|Pyribenzamine Hydrochloride|Tripelennamine|Tripelennamine HCl|Tripelennamine hydrochloride|Tripelennamine Hydrochloride|去敏灵|盐酸曲吡那敏

靶点活性

H1 receptor:30 μM

体内活性

在人和兔肝微粒体中,Tripelennamine能抑制2-amino-1-methyl-6-phenylimidazo[4,5-b]嘧啶 (PhIP)的糖脂化。

体外活性

在马匹中,静脉注射Tripelennamine HCl （0.5 mg/kg）,明显增加站立马匹混合静脉血O2压力和血红蛋白-O2饱和度,同时增加动脉和混合静脉血中O2含量,引起中枢神经系统兴奋,变得非常警觉、焦虑.

溶解度

DMSO:13 mg/mL (44.55 mM);H2O:50 mg/mL (171.34 mM)

参考文献

1.Styczynski PB, et al. Chem Res Toxicol, 1993, 6(6), 846-851.
2.Tardioli, S, et al. Journal of Raman Spectroscopy, 2011, 42 (5), 12016-1024.
3.Manohar M, et al. J Appl Physiol, 2002, 92(4), 1515-1523.
4.Wasfi IA, et al. J Vet Pharmacol Ther, 2000, 23(3), 145-152.
5.Shannon HE, et al. Pharmacol Biochem Behav, 1982, 17(4), 789-795.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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