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Tolperisone hydrochloride

CAS号

3644-61-9

分子式

C16H24ClNO

主要靶点

Sodium Channel

仅限科研使用

Cat No : CM06506

Print datasheet

Synonyms

inhibit|托哌酮盐酸盐|盐酸托哌酮|Sodium Channel|SodiumChannel|Tolperisone HCl|Tolperisone hydrochloride|Tolperisone Hydrochloride|Tolperisone|Inhibitor|Muscalm|Midocalm

验证数据展示

  • CAS No.: 3644-61-9

    Tolperisone hydrochloride
    CAS#: 3644-61-9

产品信息

CAS号 3644-61-9
分子式 C16H24ClNO
主要靶点 Sodium Channel
主要通路 离子通道
分子量 281.82
纯度 99.9%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
别名 inhibit|托哌酮盐酸盐|盐酸托哌酮|Sodium Channel|SodiumChannel|Tolperisone HCl|Tolperisone hydrochloride|Tolperisone Hydrochloride|Tolperisone|Inhibitor|Muscalm|Midocalm

体内活性

Tolperisone hydrochloride是一种安全有效的治疗疼痛反射性肌肉痉挛的药物,且没有中枢性肌肉松弛药的典型副作用。Tolperisone可以阻断蜗牛神经元的钙离子流,降低青蛙郎氏节处钠钾离子渗透性,并且对电流通过Nav1.6通道（异源表达）有抑制作用。

溶解度

Ethanol:52 mg/mL (184.51 mM);DMSO:55 mg/mL (195.16 mM);H2O:51 mg/mL (180.97 mM)

参考文献

1.Hofer D, et al. Eur J Pharmacol, 2006, 538(1-3), 5-14.
2.Pratzel HG, et al. Pain, 1996, 67(2-3), 417-425.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
=
×
×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
×
C1   V1   C2   V2