Ticlopidine

Ticlopidine (PCR 5332) 是抗血栓前药。它是CYP2C19人肝细胞色素的抑制剂,抑制 CYP2C9 及 CYP3A4。他是变构CD39的非竞争性抑制剂,能够阻断 NTPDase 同工酶,对NTPDase2和NTPDase3的IC50分别为 170 µM 和 149 µM。

CAS号

55142-85-3

分子式

C14H14ClNS

主要靶点

Adiponectin receptor|ATPase

仅限科研使用

Cat No : CM00546

Print datasheet

Synonyms

噻氯匹定|Ticlid|PCR 5332



产品信息

Ticlopidine is an antiplatelet drug in the thienopyridine family which is an adenosine diphosphate (ADP) receptor inhibitor.

CAS号 55142-85-3
分子式 C14H14ClNS
主要靶点 Adiponectin receptor|ATPase
主要通路 G蛋白偶联受体|离子通道
分子量 263.78
纯度 99.21%, 此纯度可做参考,具体纯度与批次有关系,可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 噻氯匹定|Ticlid|PCR 5332

溶解度

H2O:Insoluble,DMSO:Soluble

参考文献

1.Maffrand, JP (2012). The story of clopidogrel and its predecessor, ticlopidine: Could these major antiplatelet and antithrombotic drugs be discovered and developed today. Comptes Rendus Chimie. 15 (8): 737–743.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
=
×
×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
×
C1   V1   C2   V2