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Thalidomide-O-C6-NH2 hydrochloride

Thalidomide-O-C6-NH2 hydrochloride (4-((6-aminohexyl)oxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride) 是一种合成的E3 连接酶配体 -linker 偶联物，用于 PROTAC dTAG-13 的合成。其中 dTAG-13 是一种 FKBP12F36V 和 BET 的降解剂。

CAS号

2245697-88-3

分子式

C19H24ClN3O5

主要靶点

E3 Ligase Ligand-Linker Conjugate

仅限科研使用

Cat No : CM03875

Print datasheet

Synonyms

4-((6-aminohexyl)oxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride|萨力多胺-O-C6-氨基盐酸盐

验证数据展示

  • CAS No.: 2245697-88-3

    Thalidomide-O-C6-NH2 hydrochloride
    CAS#: 2245697-88-3

产品信息

Thalidomide-O-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate.

CAS号 2245697-88-3
分子式 C19H24ClN3O5
主要靶点 E3 Ligase Ligand-Linker Conjugate
主要通路 PROTAC
分子量 409.86
纯度 97.45%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 4-((6-aminohexyl)oxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride|萨力多胺-O-C6-氨基盐酸盐

溶解度

DMSO:83.33 mg/mL (195.19 mM),Sonification is recommended.,H2O:25 mg/mL (61.00 mM),Sonification is recommended.

参考文献

1.Erb MA, et al. Transcription control by the ENL YEATS domain in acute leukaemia. Nature. 2017 Mar 9;543(7644):270-274.

The molarity calculator equation

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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