Thalidomide 4'-ether-alkylC2-amine hydrochloride

Thalidomide 4'-ether-alkylC2-amine hydrochloride (halidomide-linker 6) 包含基于 Thalidomide 的 cereblon 配体和 linker,是合成的 E3 连接酶配体-linker 偶联物,可应用于 PROTAC 技术。

CAS号

2341840-99-9

分子式

C15H16ClN3O5

主要靶点

E3 Ligase Ligand-Linker Conjugate

仅限科研使用

Cat No : CM03874

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Synonyms

halidomide-linker 6



产品信息

Thalidomide 4'-ether-alkylC2-amine hydrochloride is a synthesized E3 ligase ligand-linker conjugate.

CAS号 2341840-99-9
分子式 C15H16ClN3O5
主要靶点 E3 Ligase Ligand-Linker Conjugate
主要通路 PROTAC
分子量 353.76
纯度 98.56%, 此纯度可做参考,具体纯度与批次有关系,可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 halidomide-linker 6

参考文献

1.Turk BE, et al. Binding of thalidomide to alpha1-acid glycoprotein may be involved in its inhibition of tumor necrosis factor alpha production. Proc Natl Acad Sci U S A. 1996;93(15):7552‐7556.

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