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Tegafur

Tegafur (FT 207) 是一种前药，在肝脏中被细胞色素 P-450 酶逐渐转化为氟尿嘧啶。它是抗代谢物氟尿嘧啶的同源物，具有抗肿瘤活性。

CAS号

17902-23-7

分子式

C8H9FN2O3

主要靶点

Nucleoside Antimetabolite/Analog|DNA/RNA Synthesis

仅限科研使用

Cat No : CM00536

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Synonyms

Fluorafur|FT-207|替加氟|FT 207|NSC 148958

验证数据展示

  • CAS No.: 17902-23-7

    Tegafur
    CAS#: 17902-23-7

产品信息

Ftorafur is a congener of the antimetabolite fluorouracil with antineoplastic activity. Ftorafur is a prodrug that is gradually converted to fluorouracil in the liver by the cytochrome P-450 enzyme.

CAS号 17902-23-7
分子式 C8H9FN2O3
主要靶点 Nucleoside Antimetabolite/Analog|DNA/RNA Synthesis
主要通路 细胞周期|DNA损伤和修复
分子量 200.17
纯度 99.95%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 Fluorafur|FT-207|替加氟|FT 207|NSC 148958

溶解度

DMSO:38 mg/mL (189.8 mM),Ethanol:7 mg/mL (34.97 mM),H2O:8 mg/mL (39.96 mM)

参考文献

1.Sotaro Sadahiro, et al. Y ChemOthersapy and Pharmacology. 2012, 70 (2): 285-291.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
=
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×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
×
C1   V1   C2   V2