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验证数据展示

  • IHC staining of mouse heart using 15444-1-AP (same clone as 15444-1-PBS)

    IHC staining of mouse heart using 15444-1-AP (same clone as 15444-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse heart tissue slide using 15444-1-AP (TSPO/PBR antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 15444-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse heart using 15444-1-AP (same clone as 15444-1-PBS)

    IHC staining of mouse heart using 15444-1-AP (same clone as 15444-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse heart tissue slide using 15444-1-AP (TSPO antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 15444-1-PBS in a different storage buffer formulation.

  • WB analysis of HEK-293 using 15444-1-AP (same clone as 15444-1-PBS)

    WB analysis of HEK-293 using 15444-1-AP (same clone as 15444-1-PBS)

    HEK-293 cells were subjected to SDS PAGE followed by western blot with 15444-1-AP (TSPO/PBR antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 15444-1-PBS in a different storage buffer formulation.

TSPO/PBR Polyclonal antibody, PBS Only

TSPO/PBR Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 15444-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IHC, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

15444-1-PBS targets TSPO/PBR in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原 TSPO/PBR fusion protein Ag7475 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 translocator protein (18kDa)
别名
计算分子量 18 kDa
观测分子量18 kDa
GenBank蛋白编号BC001110
基因名称 TSPO
Gene ID (NCBI) 706
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDP30536
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

TSPO, also named Peripheral-type benzodiazepine receptor (PBR), encodes the translocator protein, belonging to tryptophan-rich sensory protein family. The protein is mainly localized in the outer mitochondrial membrane and expressed in steroid-synthesizing tissues (PMID:32881658, PMID:1326278). TSPO is involved in the translocation of cholesterol from the outer to inner mitochondrial membrane (PMID:21119734). In response to injury, TSPO has a upregulated expression in the peripheral nervous system (PMID:32423330, PMID:23251719). TSPO is also as a biomarker in a non-invasive procedure including detecting the inflammation in the heart and atherosclerotic plaques (PMID:24402571).