TRPV1-Specific Polyclonal antibody
TRPV1-Specific Polyclonal Antibody for ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human
Applications
ELISA
Conjugate
Unconjugated
验证数据展示
产品信息
19735-1-AP targets TRPV1-Specific in ELISA applications and shows reactivity with human samples.
| Tested Applications | ELISA |
| Tested Reactivity | human |
| Immunogen | Peptide 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Full Name | transient receptor potential cation channel, subfamily V, member 1 |
| Synonyms | Capsaicin receptor, Osm 9 like TRP channel 1, OTRPC1, TRPV1, Vanilloid receptor 1, VR1 |
| Calculated Molecular Weight | 95 kDa |
| GenBank Accession Number | NM_018727 |
| Gene Symbol | TRPV1 |
| Gene ID (NCBI) | 7442 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q8NER1 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
TRPV1, also named as OTRPC1 and VR1, belongs to the transient receptor family and TrpV subfamily. TRPV1 is a receptor-activated non-selective calcium permeant cation channel involved in detection of noxious chemical and thermal stimuli. It seems to mediate proton influx and may be involved in intracellular acidosis in nociceptive neurons. TRPV1 may be involved in mediation of inflammatory pain and hyperalgesia. It is sensitized by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases, which involves PKC isozymes and PCL. This antibody is specific to TRPV1.