验证数据展示
产品信息
19735-1-AP targets TRPV1-Specific in ELISA applications and shows reactivity with human samples.
| 经测试应用 | ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 | Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | transient receptor potential cation channel, subfamily V, member 1 |
| 别名 | Capsaicin receptor, Osm 9 like TRP channel 1, OTRPC1, TRPV1, Vanilloid receptor 1, VR1 |
| 计算分子量 | 95 kDa |
| GenBank蛋白编号 | NM_018727 |
| 基因名称 | TRPV1 |
| Gene ID (NCBI) | 7442 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q8NER1 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
TRPV1, also named as OTRPC1 and VR1, belongs to the transient receptor family and TrpV subfamily. TRPV1 is a receptor-activated non-selective calcium permeant cation channel involved in detection of noxious chemical and thermal stimuli. It seems to mediate proton influx and may be involved in intracellular acidosis in nociceptive neurons. TRPV1 may be involved in mediation of inflammatory pain and hyperalgesia. It is sensitized by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases, which involves PKC isozymes and PCL. This antibody is specific to TRPV1.